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Moving microfluidics from the lab bench to the factory floor (MIT)
In the not-too-distant future, plastic chips the size of flash cards may
quickly and accurately diagnose diseases such as AIDS and cancer, as well as
detect toxins and pathogens in the environment. Such lab-on-a-chip technology
— known as microfluidics — works by flowing fluid such as blood through
microscopic channels etched into a polymer’s surface. Scientists have devised
ways to manipulate the flow at micro- and nanoscales to detect certain
molecules or markers that signal disease.
Microfluidic devices have the potential to be fast, cheap and portable
diagnostic tools. But for the most part, the technology hasn’t yet made it to
the marketplace. While scientists have made successful prototypes in the
laboratory, microfluidic devices — particularly for clinical use — have yet to
be manufactured on a wider scale.
MIT's David Hardt is working to move microfluidics from the lab to the
factory. Hardt heads the Center for Polymer Microfabrication — a
multidisciplinary research group funded by the Singapore-MIT Alliance — which
is designing manufacturing processes for microfluidics from the ground up. The
group is analyzing the behavior of polymers under factory conditions, building
new tools and machines to make polymer-based chips at production levels, and
designing quality-control ...
MIT
