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How Thyroid Problems Cause Insulin Resistance (Wellness Resource)
The plot thickens. How simple it once was for endocrinologists to identify a
few organs, like the thyroid, measure their hormones, and then prescribe
hormone replacement when seemingly lacking in them. While this method may have
been easier, it was often not very helpful in solving the obvious thyroid
problems that many experience.
In 1994 that simplicity changed forever. With the discovery of the hormone
leptin and the fact that the adipocyte, fat cell, was busy not only making
leptin but also making many other hormonal signals, this picture takes on even
more complexity. It is now clear that your muscle cells, myocytes, are also
making hormonal signals that cross-talk with your fat cells and your thyroid.
Anyone for a game of chess?
Insulin resistance comes in many shapes and sizes. At the cellular level,
cells that are having too many calories stuffed into them shut the door to
keep calories out; this is a key method of self-preservation. Slamming the
door means taking down the receptor for insulin on the surface of the cell,
which prevents the taxicab known as insulin from dropping off its passengers
(sugar).
Insulin resistance can happen at the site of ...
Wellness Resource